The Helsinki Declaration is the ‘gold standard’ — a directive, not a law, on how to conduct controlled studies in humans in conformity with ethical principles. In spite of many discussions about their unsuitability some articles have remained unchanged in the most recent (sixth) revision of the Declaration. The demand to use “the best treatment” excludes use of placebo in the control group and presents an obstacle to the scientific evaluation of a number of drugs and treatments in general. The (...) use of placebo is justified whenever its use does not cause irreversible damage or considerable suffering to the well informed patient. It must be, is, and will be used in the controlled clinical trials of treatments of a great number of diseases especially those which have a tendency to spontaneous improvement, even healing, or have a pronounced psychological component. (shrink)

There is an emerging awareness of the possibility of conflicts of interest in the practice of medicine in Croatia. The paper examines areas within the medical profession where conflicts of interest can and have occurred, probably not only in Croatia. Particularly addressed are situations when a doctor may have dual obligations and how independent ethics committees can help in decreasing the influence of a conflict of interest. The paper also presents extracts from the Croatian Code of Ethics for the medical (...) profession that address problems of conflict of interest. (shrink)

There is an emerging awareness of the possibility of conflicts of interest in the practice of medicine in Croatia. The paper examines areas within the medical profession where conflicts of interest can and have occurred, probably not only in Croatia. Particularly addressed are situations when a doctor may have dual obligations and how independent ethics committees can help in decreasing the influence of a conflict of interest. The paper also presents extracts from the Croatian Code of Ethics for the medical (...) profession that address problems of conflict of interest. (shrink)

The Helsinki Declaration is the ‘gold standard’ — a directive, not a law, on how to conduct controlled studies in humans in conformity with ethical principles. In spite of many discussions about their unsuitability some articles have remained unchanged in the most recent (sixth) revision of the Declaration. The demand to use “the best treatment” excludes use of placebo in the control group and presents an obstacle to the scientific evaluation of a number of drugs and treatments in general. The (...) use of placebo is justified whenever its use does not cause irreversible damage or considerable suffering to the well informed patient. It must be, is, and will be used in the controlled clinical trials of treatments of a great number of diseases especially those which have a tendency to spontaneous improvement, even healing, or have a pronounced psychological component. (shrink)

An increasing body of evidence indicates that the response to genotoxic agents such as radiation or drugs is a group phenomenon, rather than the summed response of individual independent cells to injury. Thus, a complex contagion-like response may spread beyond the initial impact of an agent to enlarge its effect. This indirect effect, termed “Bystander Effect,” is multifaceted and may play a significant role in the therapy of tumors and in carcinogenesis. A better understanding of this phenomenon is needed in (...) order to modulate treatment protocols to therapeutic advantage and to provide more rational guidelines for the evaluation of environmental hazards. BioEssays 22:286–290, 2000. © 2000 John Wiley & Sons, Inc. (shrink)

Rad ukazuje na kljucne momente razvoja teorije aktera-mreze kroz nekoliko najznacajnih dela Bruna Latura. Uocavaju se promene pocetne pozicije autora u odnosu na dela kasnijeg datuma nastanka. Teorija aktera-mreze je prikazana kroz niz?neuralgicnih? tacaka koje se u njoj mogu uociti. Na samom kraju rada su razmatrana resenja koje teorija aktera-mreze nudi za odredjeni broj fundamentalnih problema sociologije, koje je definisao Latur.

We present the basic concepts of space and time, the Galilean and pseudo-Euclidean geometry. We use an elementary geometric framework of affine spaces and groups of affine transformations to illustrate the natural relationship between classical mechanics and theory of relativity, which is quite often hidden, despite its fundamental importance. We have emphasized a passage from the group of Galilean motions to the group of Poincaré transformations of a plane. In particular, a 1-parametric family of natural deformations of the Poincaré group (...) is described. We also visualized the underlying groups of Galilean, Euclidean, and pseudo-Euclidean rotations within the special linear group. (shrink)

Horgan believes that the truth of the statement “Beethoven’s fifth symphony has four movements” does not require that there be some “dedicated object” answering to the term “Beethoven’s fifth simphony”. To the contrary, the relevant language/world correspondence relation is less direct than this. Especially appropriate is the behavior by Beethoven that we would call “composing his fifth symphony”. Our objections go along two directions: (1) is the process ontology (a) really a right kind of ontology for artworks (symphonies, novels) and, (...) (b) more important, is this kind of ontology compatible with Parmenidian approach to ontology? The answer to (a) is negative. With reference to point (1b) we might say that Parmenides was a typical staunch advocate of substance metaphysics rather than process metaphysics. Traditionally, substances are individuated by their properties, namely, there are assumed two sorts of properties: primary and secondary. Primary properties describe the substance as it is in and by itself; secondary properties underlie the impact of substances upon others and the responses they elicit from them. (2) The claim that it is most unlikely to suppose that we can have some kind of cognitive contact “with an entity which has no spatio-temporal location and does not causally interact with anything” does not hold. We underpin the claim that there is some cognitive access to entity such as Beethoven’s fifth symphony with Bender’s theory of realization relation between musical work and performance. (shrink)

There is widespread view among numerous aestheticians that aesthetic and value properties are response-dependent. According to some philosophers the dependence has a rich and multilayered structure: value qualities (e.g. beauty) depend on our response to aesthetic properties (e.g. harmonious), which in turn depend on our response to a pattern of primary and secondary qualities (shapes and colors). Secondary qualities are themselves response-dependent. The basic dependence relation is thus iterated. The resulting structure is one of iterated response-dependence. The integral part of (...) such a position is a relational view, best captured by the response-dispositional analysis: My states of being appeared to magnificently in front of a painting manifests the disposition of painting to induce such experience in the normal viewer.There are two main objections against the dispositional analysis: (1) argument from circularity and (2) argument from introducing two kinds of quality, one categorical, for experiential states, and one dispositional for objects. In this paper we will suggest the arguments against second objection. (shrink)

The paper deals with the topic of empty terms as considered in chapter six of Devitt’s book Designation. Devitt’s proposal is that a statement about fiction is (usually) implicitly preceded by a fiction operator roughly paraphrasable by “it is pretended that” or “in fiction”. The causal chain that forms the network for a fictitious name are not d(esignational)-chains, for they are not grounded in an object. Nevertheless, although the fictitious name does not designate, we could say that it stands in (...) some other referential relationship to the world: it ‘F(ictionally)-designates’. It seem that we could then state truth conditions of a F-sentence using F-designation: the F-operator direct us to look not for the designatum of name but for its F-designatum. The name (for example, “Napoleon” in War and Peace), though nonempty, is just like a fictitious name. In proposing that nonempty names in fiction refer to real items, I argue against the view that “Napoleon” in the War and Peace designates the famous general, Napoleon, and F-designates parts of War and Peace. The referent of F-designation is Napoleon, famous general, too. At the end of the paper I claim that Devitt, if he wants to remain a modal fictionalist, has to renounce the view of one-world metaphysics. (shrink)

The author?s approach is based on three premises: 1. that Gajo Petrovic?s Praxis was an outstanding phenomenon in Croatian, Yugoslav and European culture, a challenge of freedom in a repressive society; 2. that there has never been such a thing as "Praxis group", "philosophers of practice" or "Praxis philosophers" with a unified philosophical and socio-theoretical orientation; and 3. that political and ideological attacks on Praxis were part of the repressive system that targeted every instance of cultural and scientific dissent. The (...) political leadership of Tito?s regime, its ideological and propaganda apparatus systematically disseminated allegations, denunciations and accusations against Praxis and Gajo Petrovic. The same style has survived through radical historical changes from the appearance of Praxis until today. The attackers have often been the same persons, with the difference that in earlier times they denounced Praxis and Gajo Petrovic as enemies of "socialism" and the "socialist self-management system", and in the changed political fashion as "servants" of Tito?s authoritarian rule. The fate of Praxis in the former regime has been triumphantly interpreted as a "family quarrel". This paper attempts a sociological analysis of the political destiny of Praxis. The analysis is essentially determined not by old and new political and ideological questionings of Praxis, but by Gajo Petrovic?s fundamental belief that there is no freedom without the human or humanity without freedom.. Osnovu autorovog pristupa cine tri stava: 1. da je Praxis Gaje Petrovica bio izuzetna pojava u hrvatskoj, jugoslovenskoj i evropskoj kulturi, izazov slobode u drustvu represije; 2. da ne postoji tako nesto kao "praxis-grupa", "filozofi prakse" ili "praxis filozofi" koji bi imali jedinstvenu filozofsku ili drustveno-teorijsku orijentaciju; 3. da su politicka i ideoloska osporavanja Praxisa bila deo represivnog sistema kojem je bilo podvrgnuto svako neistomisljenistvo u kulturi i nauci. Politicki vrh Titovog rezima, njegov ideoloski i propagandni aparat sistematski su sirili insinuacije, denuncijacije i optuzbe o Praxisu i Gaji Petrovicu, da bi taj manir u bitno promenjenim istorijskim okolnostima, trajao od pojave Praxisa do danasnjeg dana. Cesto su i akteri napada bile iste osobe, samo sto su nekada osporavali Praxis i Gaju Petrovica kao neprijatelje "socijalizma" i "sistema socijalistickog samoupravljanja", a u promenjenoj politickoj modi kao "sluge" Titove autoritarne vladavine. Sudbinu Praxisa u prethodnom rezimu slavodobitno su tumacili kao "obracun u obitelji". Rad je pokusaj socioloske analize politicke sudbine Praxisa, koju ce bitno odrediti temeljno uverenje Gaje Petrovica da nema slobode bez coveka ni ljudskosti bez slobode, a ne stara i nova politicka i ideoloska osporavanja Praxisa.. (shrink)

En tant que communaut? ethnique et groupe social d?favoris?, les Roms se heurtent quotidiennement aux probl?mes relatifs r l?obtention de papiers d?identit? ou autres documents, difficult? qui les prive de leur?galit? devant l?ensemble des citoyens, et les rend m?me inexistants. L?objet de cet te recherche porte sur les d?marches et probl?mes rencontr?s par les demandeurs en vue d?obtenir les documents suivants: a) num?ro d?immatriculation; b) extrait d?acte de naissance, dedans, de mariage; c) certificat de nationalit?; d) d?claration de s?jour et (...) de lieu de r?sidence; e) carte d?identit? et carte de travail, alors que les groupes vis?s par la recherche sont: employ?s et responsables d?offices d??tat civil; demandeurs, interm?diaires avec autorisations, militants roms et leurs associations, commissaires pour les r?fugi?s et personnes d?plac?es, fonctionnaires de certaines communes et secr?taires des communes, repr?sentants de MUP. Nous avons analys? le travail et les difficult?s de travail de certains organismes, ainsi que les probl?mes rencontr?s par les demandeurs et les interm?diaires avec autorisations en vue de se voir d? livrer des documents personnels ou lors des proc?dures d?obtention de documents personnels. En dernier lieu, nos recommandations concernent l?organisation et la coordination des organismes d??tat civil, une meilleure information s?adressant aux demandeurs, et contiennent le concept d?une am?lioration syst?matique de cet?tat de choses visant r ce que les roms de viennent des citoyens?gaux.. Kao deprivirana etnicka zajednica i socijalna grupa Romi se suocavaju u svakodnevnom zivotu sa problemima pribavljanja osnovnih licnih dokumenata, bez kojih su ne samo neravnopravni, nego cesto i neegzistentni gradjani. Predmet istrazivanja su bili postupci i problemi u sticanju sledecih dokumenata: a) jedinstveni maticni broj gradjana; b) izvodi iz maticnih knjiga rodjenih, umrlih, vencanih; c) uverenja o drzavljanstvu; d) prijava boravka i prebivalista e) licne karte i rad ne knjizice, a osnovne ciljne grupe istrazivanja bili su: sluzbenici i rukovodioci izmestenih maticnih ureda; neposredni podnosioci zahteva za izdavanje dokumenata; posrednici sa ovlastenjima ; romski aktivisti i udruzenja, javni zastupnici, poverenici za izbegli ce i raseljena lica; nacelnici pojedinih opstinskih sluzbi i sekretari opstina, predstavnici MUP-a. Analiziran je rad i poteskoce u radu maticnih i drugih sluzbi, problemi neposrednih podnosilaca zahteva za izdavanje nekog od licnih dokumenata i, posrednici sa ovlascenjima. Na kraju je u preporukama o organizaciji i koordinaciji rada maticnih sluzbi, preporukama za bolje informisanje Roma, podnosilaca zahteva i preporukama u korist podnosilaca zahteva sadrzan koncept sistematskog poboljsanja stanja, cime bi se Romima omogucilo da budu istinski ravnopravni gradjani Srbije. (shrink)

Romi su veoma disperzirana etnicka zajednica. Od kako je nad Kosovom uspostavljen medjunarodni protektorat, Romi su najbrojnija nacionalna manjina u Jugoslaviji. Kada se govori o diskriminaciji i integraciji Roma, treba imati u vidu da su do sada najcesce bili izlozeni negativnim vidovima diskriminacije, a da je integracija cesto znacila fakticku asimilaciju. Kako postoji i pozitivna diskriminacija manjinskih grupa u drustvu, ocigledno je da u osnovni pristup 'romskom pitanju' podrazumeva strateski obrat ponasanja svih drzavnih institucija i drugih drustvenih cinilaca od negativne (...) ka pozitivnoj diskriminaciji i od asimilacije ka istinskoj integraciji Roma. Osnovni pristup za koji se autor zalaze je onaj koji omogucava Romima da budu nasi ravnopravni sugradjani. Krugovi bede u kojima se nalazi romsko stanovnistvo postaju sve dublji. Medjutim, carstvo bede se siri jugoslovenskim prostorom. Osiromasenje je opste. Devastacija uslova zivota za sve gradjane Jugoslavije, odnosno Srbije i Crne Gore, izuzev uskog kruga ratnih profitera i ljudi iz centara moci, traje vise od jedne decenije. Srednji slojevi su nestali sa drustvene scene, a mnoge porodice su dosle u subproletersku zonu siromastva. (shrink)

Autor analizira stavove intelektualaca s podrucja bivse Jugoslavije, okupljenih oko casopisa Praxis, prema nacionalizmu, kao i kritike koje su im upucivali nacionalisti, pre svega iz Hrvatske i Srbije. Analiza obuhvata period od pojave Praxisa do prve decenije dvadeset prvog veka.

On the basis of his own previous research the author examines views of Europe held by the Serbian political and cultural elite in the late 20th and early 21st century. Unable to meet the challenges of the historical moment, this elite has brought Serbia into open conflict with its closest neighbors and exposed its citizens to international sanctions. War-mongering propaganda of the major state-controlled media was developing feelings of xenophobia and frustration among citizens. The collusion between authoritarian government and war (...) profiteers was systematically destroying the lives of Serbian citizens, bringing them to the brink of material impoverishment and spiritual misery. The process of dissolution of the common Yugoslav state is coming to its end in the first decade of this century. Just as it lacked wisdom political will or strength to prevent armed conflicts and crimes, the Serbian elite today is unable to condemn war crimes, to face disastrous consequences of its own policies, and to help Serbian citizens find their way to prosperity. (shrink)

Pregledujem sedanje slepe ulice zahodne filozofije in predlagam nov začetek. V sedanjem trenutku prevladujejo tri najmočnejše pojmovne opcije; skepticizem, kognitivni privilegij in historicizem. Prvi je škandal, drugega zavračajo vse strani, tretji pa je trenutno dokaj zanemarjen. Historicizem ali zgodovinskost - pojem, daje mišljenje notranje historizirano, da je mišljenje zgodovina - je edini velik nov prispevek moderne filozofije k glavnim pojmovnim virom zahodne tradicije. Sodobna filozofija, posebno angloameriška analitična filozofija, je v bistvu nadaljevanje filozofije 17. stoletja in predkantovske filozofije 18. stoletja, (...) ki ju begajo »nepomembnosti« 19. stoletja; kontinentalna filozofija, v glavnem francoska in nemška, pa se je zdaj pripravljena prilagoditi ahistoricizmu analitične filozofije. Predlagam ponovno odkritje historicizma in prepoznam številne različne strategije, ki dajejo prednost taki politiki, za katero napovedujem, da bo še enkrat prišla na vrsto v naslednjem stoletju. Še posebej skrbno raziskujem vidike prve filozofije, zaprtih sistemov, rešitev problemov reference in predikacije, odnos med naravo in kulturo, odnos med realizmom in idealizmom in naravo ter funkcijo osebe ali sebstva. Ugotavljam, da se sodobna filozofija mora spoprijeti s prispevki Kantovega konstruktivizma in Heglove simbioze in iti preko obeh. Med dokazovanjem orišem splošno krivuljo zahodne filozofije vse do današnjih časov. (shrink)

The topic of this paper is the role played by context in art. In this regard I examine three theories linked to the names of J. Levinson, G. Currie and D. Davies. Levinson’s arguments undermine the structural theory. He finds it objectionable because it makes the individuation of artworks independent of their histories. Secondly, such a consequence is unacceptable because it fails to recognise that works are created rather than discovered. But, if certain general features of provenance are always work-constitutive, (...) as it seems that Levinson is willing to claim, these features must always be essential properties of works. On the other hand, consideration of our modal practice suggests that whether a given general feature of provenance is essential or non-essential depends upon the particular work in question or is “work relative”. D. Davies builds his performance theory on the basis of the critical evaluation of Currie’s action-type hypotheses (ATH). Performances, says Davies, are not to be identified with “basic actions” to which their times belong essentially, but with “doings” that permit of the sorts of variation in modal properties required by the work-relativity of modality. He is also a fierce critic of the contextualist account. Contextualism is in his view unable to reflect the fact that aspects of provenance bear upon our modal judgements with variable force. In the second part of the paper I consider Davies’s “modality principle”. Davies is inclined to defend the claim that labels used for designation of works are rigid designators. Such a view offers a ground for discussion about the historicity of art. What has been meant when people claim that art is an historical concept? I argue that any historical theory implies a two-dimensional notion of “art”. At the end of the paper I suggest that Davies should embrace the theory of contingent identity and not the colocationist view about the relationship that exists between a particular artwork and its physical bearer. (shrink)

This book traces the growth of philosophical justifications of toleration. The contributors discuss the grounds on which we may be required to be tolerant and the proper limits of toleration. They consider the historical and conceptual relation between toleration and scepticism and ask whether toleration is justified by considerations of autonomy or of prudence. The papers cover a range of perspectives on the subject, including Marxist and Socialist as well as liberal views. The editor's introduction prepares the ground by discussing (...) the essential features of the subject and offers a lucid survey of the theories and arguments put forward in the book. The collection arises out of the Morrell Toleration Project at the University of York and all the papers were written as contributions to that project. The discussion will be of interest to specialists in philosophy, in political and social theory and in intellectual history. (shrink)

A distinction is made between moral indoctrination and instruction in ethics. It is argued that the legitimate and important field of computer ethics should not be permitted to become mere moral indoctrination. Computer ethics is an academic field in its own right with unique ethical issues that would not have existed if computer technology had not been invented. Several example issues are presented to illustrate this point. The failure to find satisfactory non-computer analogies testifies to the uniqueness of computer ethics. (...) Lack of an effective analogy forces us to discover new moral values, formulate new moral principles, develop new policies, and find new ways to think about the issues presented to us. For all of these reasons, the kind of issues presented deserve to be addressed separately from others that might at first appear similar. At the very least, they have been so transformed by computing technology that their altered form demands special attention. (shrink)

John Bintliff et alii Le Tanagra Project : recherches dans une cité antique de Béotie et son territoire (2000-2002) p.541-606 Cet article présente les résultats préliminaires du Leiden-Ljubljana Field Project dans la cité antique de Tanagra, en Béotie orientale, et dans ses environs immédiats. Les travaux ont débuté en 1999, avec une vaste équipe de chercheurs et d'étudiants des Pays-Bas, de Belgique, de Slovénie et de Grèce, sous la direction de John Bintliff et Bozidar Slapsak et la sous-direction de (...) Kostas Sbonias. Les différents spécialistes présentent ici leur travail en détail, développant les rapports des deux premières campagnes publiés dans Pharos, le périodique annuel de l'Institut néerlandais d'Athènes. (shrink)

The idea that reasoning is a singular accomplishment of the human species has an ancient pedigree.Yet this idea remains as controversial as it is ancient. Those who would deny reasoning to nonhuman animals typically hold a language-based conception of inference which places it beyond the reach of languageless creatures. Others reject such an anthropocentric conception of reasoning on the basis of similar performance by humans and animals in some reasoning tasks, such as transitive inference. Here, building on the modal similarity (...) theory of Vigo [J Exp Theor Artif Intell, 2008 (in press)], we offer an account in which reasoning depends on a core suite of subsymbolic processes for similarity assessment, discrimination, and categorization. We argue that premise-based inference operates through these subsymbolic processes, even in humans. Given the robust discrimination and categorization abilities of some species of nonhuman animals, we believe that they should also be regarded as capable of simple forms of inference. Finally, we explain how this account of reasoning applies to the kinds of transitive inferences that many nonhuman animals display. (shrink)

The use of role-playing (“active learning”) as a teaching tool has been reported in areas as diverse as social psychology, history and analytical chemistry. Its use as a tool in the teaching of engineering ethics and professionalism is also not new, but the approach develops new perspectives when used in a college class of exceptionally wide cultural diversity. York University is a large urban university (40,000 undergraduates) that draws its enrolment primarily from the Greater Toronto Area, arguably one of the (...) most culturally diverse cities in the world, embracing the largest percentage of Canada’s immigration. Among the area’s five million inhabitants, 50% identify themselves as a visible minority born outside Canada, while over 100 languages and dialects are spoken daily. Although students admitted from this international pool have usually been exposed to western attitudes during secondary education and are rapidly assimilated into Canadian culture, responses to specific ethical issues are strongly influenced by their prior culture. Two and three-part scripts for case studies based on NSF or original scenarios were written to illustrate issues such as gifts, attitudes towards women and ethnic minorities, conflict of interest, whistle-blowing, sexual harassment, individual rights, privacy, environment, intellectual property, and others. Following the presentation, the actors lead group discussion based on previously specified questions. Once the initial shyness and reluctance of some cultures has been overcome through the building of rapport, students have written original scripts based on hypothetical or prior personal situations. The method is now being adopted in a short course format to assist the professional integration of foreign trained engineers. (shrink)

How are Chinese philosophy and analytic philosophy-two very distinct traditions-alike? In this volume, fifteen distinguished scholars compare and contrast the methodologies, finding areas in which each tradition can learn from, contribute to, and complement the other.

Scientific editors’ policies, including peer review, are based mainly on tradition and belief. Do they actually achieve their desired effects, the selection of the best manuscripts and improvement of those published? Editorial decisions have important consequences—to investigators, the scientific community, and all who might benefit from correct information or be harmed by misleading research results. These decisions should be judged not just by intentions of reviewers and editors but also by the actual consequences of their actions. A small but growing (...) number of studies has put editorial policies to a strong scientific test. In a randomized, controlled trial. blinding reviewers to author and institution was usually successful and improved the quality of reviews. Two studies have shown that, contrary to conventional wisdom, reviewers early in their careers give better reviews than senior reviewers. Many studies have shown low agreement between reviewers but there is disagreement about whether this represents a failing of peer review or the expected and valuable effect of choosing reviewers with complementary expertise. In a study of whether manuscripts are improved by peer review and editing, articles published in Annals of Internal Medicine were improved in 33 of 34 dimensions of reporting quality, but published articles still had room for improvement. Because of the central place of peer review in the scientific community and the resources it requires, more studies are needed to define what it does and does not accomplish. (shrink)

In this article, we focus on the mentoring process, and we argue that the internal and external pressures extant at research universities may create a research culture that may be antithetical to appropriate mentoring. We developed a scale based on motivation theory to determine the perceived research culture in departments and research laboratories, and a mentoring scale to determine approaches to mentoring graduate students. Participants were 610 faculty members across 49 departments at a research oriented university. The findings were that (...) a mastery-oriented research climate and an outcome-oriented research climate were manifested at the university. More importantly, each research climate had its own unique impact on how the faculty approached mentoring graduate students. A mastery research climate was related to a more supportive approach to mentoring than the outcome research climate. We concluded by suggesting that the outcome research climate may have an adverse effect on effective mentoring and on maintaining research ethics. (shrink)

Leading scholars explore the later thought of Merleau-Ponty and its central role in the modernism-postmodernism debate.

Professor King's concept of the philosophy of history leads him to offer this demonstration of the incoherence, even absurdity, of the notion that the past can have nothing to teach us - whether posed by those who argue that history is "unique" or that it is merely "contextual".